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1.
BMC Infect Dis ; 24(1): 218, 2024 Feb 19.
Artigo em Inglês | MEDLINE | ID: mdl-38373919

RESUMO

BACKGROUND: Fusobacterium necrophorum (F. necrophorum)-induced necrotizing pneumonia is a rare but severe pulmonary infection. Insufficient microbiological detection methods can lead to diagnostic difficulties. METHODS: We report a case of F. necrophorum lung abscess diagnosed by next-generation sequencing (NGS) of bronchoalveolar lavage fluid (BALF). RESULTS: BALF-NGS detected F. necrophorum, guiding subsequent targeted antibiotic therapy. With active drainage and metronidazole treatment, the patient's condition was effectively treated. CONCLUSION: BALF-NGS is a valuable tool for the rapid diagnosis of infections caused by difficult-to-culture bacteria. It played a decisive role in the early identification of F. necrophorum, enabling timely and targeted antibiotic intervention. Early diagnosis and appropriate treatment are crucial for the management of F. necrophorum pneumonia.


Assuntos
Infecções por Fusobacterium , Abscesso Pulmonar , Humanos , Fusobacterium , Líquido da Lavagem Broncoalveolar , Abscesso Pulmonar/diagnóstico , Abscesso Pulmonar/tratamento farmacológico , Infecções por Fusobacterium/diagnóstico , Infecções por Fusobacterium/tratamento farmacológico , Infecções por Fusobacterium/microbiologia , Antibacterianos/uso terapêutico , Fusobacterium necrophorum , Sequenciamento de Nucleotídeos em Larga Escala
2.
Pulm Circ ; 14(1): e12332, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38174160

RESUMO

Scimitar syndrome is a rare congenital anomaly characterized by partial or total anomalous pulmonary venous drainage of the right lung to the inferior vena cava. We report a case of a 67-year-old female who presented with cough and dyspnea and was diagnosed with scimitar syndrome and pulmonary arterial hypertension based on comprehensive imaging and hemodynamic evaluation. This case highlights the importance of considering scimitar syndrome as a cause of pulmonary hypertension even in adult patients.

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